Immunohistochemistry Kits and Reagents
Biotium Desmin (Muscle Cell Marker)(D33), Biotin conjugate, 0.1mg/mL
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF
Biotium CDw78(DF1588), CF594 conjugate, 0.1mg/mL
This antibody reacts with a carbohydrate determinant, identified as CDw78 (Workshop V; Code CDw78.2). Epitope recognized by this MAb and Leu21 is the same. It is present on some immature and some peripheral blood B cells, and some B cell lines. Its expression is increased after B-cell activation in vitro. CDw78 is also found on tissue macrophages and on epithelial cells, but not on T cells, NK cells, monocytes, granulocytes and myeloid tissues. It appears that CDw78 is a determinant on a major histocompatibility complex (MHC) class II subpopulation.
Abcam 20 x TBS-T with Tween 20, 125ML
Tris Buffered Saline (TBS) wash buffer with Tween 20 for use during immunolabeling techniques such as IHC.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 3D Tissue Staining Pots ( x 10) – CUBIC, 1PACK
3D Tissue Staining Pots (x10) – CUBIC (ab316247) is part of the reagents, controls & accessories range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.
The product is subject to the following: Abcam Restricted Use Statement
Biolegend TotalSeqTM-Bn0196 anti-human C
TotalSeq™-Bn0196 anti-human CD235ab [HIR2]; Isotype: Mouse IgG2b, κ; Reactivity: Human; Apps: SB; Size: 10 μg
Cayman Chemical p38 MAPK PhosphoThr180 Tyr18
Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Thr180 and phospho-Tyr182 of rat p38 MAPK • Host: rabbit • Cross Reactivity: (+) human p38 MAPK • Application(s): WB • p38 MAPK is activated by both inflammatory cytokines and by stress. It is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
Enzo Life Sciences HIGHDEF yellow IHC chromogen (HRP) (30 ml)
Unique high definition yellow IHC chromogen for HRP-activated development. HIGHDEF yellow IHC chromogen (HRP) is intended to be used in conjunction with horseradish peroxidase (HRP)-based immunostaining or in situ hybridization systems. With at least 1 day working stability, this substrate/chromogen system can be used in any automation system as well as manual use. Contents: HIGHDEF yellow IHC chromogen (HRP) substrate buffer and chromogen, Empty mixing bottle. Application: IHC, ISH (in situ hybridization). Long Term Storage: +4°C
Biogenex Laboratories Negative Control Sera/Immunoglobulins
Since each staining run should include a negative control slide to confirm reagent specificity, we offer negative control sera/immunoglobulins which have been optimized for use as negative controls for our Super Sensitive detection systems and ready-to-use antibodies. These controls are available for mouse, goat, rat and rabbit antibodies.
Leica Biosystems PV POLY-HRP M 110 DAB KIT
PowerVision Poly-HRP anti-Rabbit IHC Detection Systems are biotin-free, polymeric horseradish peroxidase (HRP) conjugated systems, for the manual detection of tissue-bound rabbit antibodies.
Abcam DAB Substrate Kit
DAB Substrate Kit
The product is subject to the following: Abcam Restricted Use Statement
![Genetex Inc UPK1A Monoclonal Antibody [MSVA-735M] HistoMAX™ (GTX04462) GeneTex - IHC-Optimized Antibody.](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3667743.jpg-250.jpg)
Genetex Inc UPK1A Monoclonal Antibody [MSVA-735M] HistoMAX™ (GTX04462) GeneTex - IHC-Optimized Antibody.
The UPK1A antibody [MSVA-735M] HistoMAX™ (GTX04462) is a Mouse Monoclonal antibody in the GeneTex HistoMAX portfolio. The antibody is extensively evaluated for IHC-P using formalin-fixed human normal tissues (more than 70 different sections) and cancer tissue arrays to guarantee specificity and best-in-class performance. Information regarding both manual and autostainer staining protocols are available.Figure Legend: IHC-P analysis of human mucosa from rectum tissue using GTX04462 UPK1A antibody [MSVA-735M] HistoMAX. Complete absence of UPK1A immunostaining in rectal mucosa.
Invivogen Purified Lipoteichoic acid from S. aureus (LTA-SA), 5mg
Specificity: TLR2 agonist, Working concentration: 1 ng -1 μg/ml, Endotoxin level: EndoFit™, Lipoteichoic acid (LTA) is a major immunostimulatory component of Gram-positive bacteria. Like LPS, LTA is an amphiphile formed by a hydrophilic polyphosphate polymer linked to a neutral glycolipid. LTA stimulates immune cells through TLR2 to produce TNF-α and other inflammatory cytokines. Recognition of LTA involves also LPS-binding protein (LBP) and CD14.
ABclonal Technology Phospho-SQSTM1/p62-S349 Rabbit pAb
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
ABclonal Technology TFF1/pS2 Rabbit mAb
Members of the trefoil family are characterized by having at least one copy of the trefoil motif a 40-amino acid domain that contains three conserved disulfides They are stable secretory proteins expressed in gastrointestinal mucosa Their functions are not defined but they may protect the mucosa from insults stabilize the mucus layer and affect healing of the epithelium This gene which is expressed in the gastric mucosa has also been studied because of its expression in human tumors This gene and two other related trefoil family member genes are found in a cluster on chromosome 21
ABclonal Technology Periostin Rabbit mAb
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms.